KING EDWARD MEMORIAL HOSPITAL

Seth Gordhandas Sunderdas Medical College

Acharya Donde Marg, Parel,
Mumbai 400 012. India.
Tel.: 91-22-2410 7000 Fax: 91-22-2414 3435

Biochemistry and Clinical Nutrition

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Background History

In 1959, Biochemistry specialty born without individual existence under Department of Physiology.

In 1973, Biochemistry arose as an independent section under the wings of the Department of Physiology. It was located on 2nd Floor, College Building, Seth GSMC & KEM Hospital, Parel, Mumbai.

Later third floor of the college building was built and Department of Physiology was shifted with Biochemistry Section to the 3rd floor.

Later in 1978, Dr. K. G. Tanksale, took over as the first HOD of an independent Department of Biochemistry, which was weaned off from Department of Physiology. Biochemistry became an individual specialty subject for First MBBS.

The initial staff included stalwarts in Biochemistry – Dr. K. G. Tanksale, Dr. P. Modi, Dr. Kumana (Engineer), Dr.A.V.Potnis, Dr. V. L. Patil, Dr. Tembe,Mrs.M. Kamath, Mr. Rajadhyaksha, Dr. B. S. Kulkarni and Dr. N. G. Magar.

In the past years, the laboratory services were catered through a central laboratory (Lab 44) which included all three specialties Pathology, Microbiology and Biochemistry. Sustained and extensive efforts by Dr. K. G. Tanksale, resulted in the formation of CCBL (Central Clinical Biochemistry Laboratory) as separate biochemistry specialty laboratory. Dr. B. S. Kulkarni was in-charge of CCBL. He had extensive knowledge of laboratory instrumentation and hence MCGM took an initiative to create one additional post of Professor for him in the CCBL.

Dr. N. G. Magar was involved in extensive research on lipids.Dr. K. G. Tanksale retired in 1990 and Dr. A. V. Potnis took over.Dr. A. V. Potnis retired in 1996 and Dr. S. P. Dandekar took over.

In 1998, as per MCI Amendment, Biochemistry was started with one separate examination paper as compared to two examination papers in Anatomy and Physiology.

The Department of Biochemistry in Seth GS Medical College & KEM Hospital had the privilege to conduct three National Conferences by ACBI (Association of Clinical Biochemists of India) along with numerous workshops, seminars and CMEs.

  • 5th ACBI National Conference was organized by Dr. K. G. Tanksale in 1979.
  • 16thACBI National Conference was organized by Dr. A. V. Potnis in 1990.
  • 37thACBI National Conference was organized by Dr. S. P. Dandekar in 2010.

Currently, Department of Biochemistry is equipped with high end fully automated biochemistry analyzers details of which are given under services.

Sections Units Branches

Clinical Laboratory

Central clinical Biochemistry Laboratory and Emergency services.

Location:

Post-Mortem Building,first floor at the Central Clinical Biochemical Laboratory, a total of nearly 700 blood Samples, from 42 general wards, 6 intensive care units and 6 different OPDs are processed every day. About 4000 different biochemical tests are carried out.

Instruments available:

  • Hitachi 911-commisioned in 1997
  • Express 550-two machines commsisioned in 1991.
  • Ciba Corning 664 for electrolytes commision in 1991.
  • Electrolyte easy-commisionead in 1998.
  • Colorimeters for manual estimations.
  • Flame photometers.
  • Research Activities.
  • The department is recognised for M.Sc.(Papers), M.Sc.(Research) & Ph.D degree programmes.
  • Research is carried out in the dept with the collaboration of other departments of the institution.

Staff

Teaching Staff

Sr No Name of the Teacher Post Held Email Address Contact  Nos
Mobile Residence
1 Dr. S. P. Dandekar Prof. & Head suchetad@hotmail.com 9821076406 02223535331
2 Dr. S. R. Prabhu Professor prabhusurekha@gmail.com 9833158335 02226351349
3 Dr. A. B. Kale Professor anitachalak@rediffmail.com 9004997705 9850620123
4 Dr. U. H. Shinde Addl. Prof. umas8586@gmail.com 9869115856 9594385398
5 Dr. R. S. Dhamnaskar Addl. Prof. rekhadhamnaskar@yahoo.co.in 9920482023 02224371614
6 Dr. C. A. Sathe Assoc. Prof. drcasathe@yahoo.com 9820450880 02224015785
7 Dr. S. A. Rane Assoc. Prof. drsarane@rediffmail.com 9930105732 02225905682
8 Mrs. G. V. Phatarphekar Assoc. Prof. phatarp@gmail.com 9820045522 02228780509
9 Dr.  Y. R. Pawade Assist. Prof yogeshpawade@gmail.com 7506036750 —–
10 Dr. K. G. Sorte Assist. Prof krantigawali@rediffmail.com 9370663730 —–
11 Dr. S. S. Fupare Assist. Prof drsantoshfupare@rediffmail.com 9552507844 —–
12 Dr. K. K. Ghosh Assist. Prof kinjalka@gmail.com 8451913854 —–
13 Dr. T. D. Ramteke Assist. Prof drtruptiumesh@gmail.com 9921335150 —–
14 Dr. Abhjit Ninghot Assist. Prof abhininghot@gmail.com 9823759521 —–

Activities of the Department

Scope of Department of Biochemistry can be broadly categorized as follows:

  • Academics
  • Research
  • Patient Care

1 .Academics:

  • The Department of Biochemistry is involved in teaching of various undergraduate and postgraduate courses viz. MBBS, BPTh, BOTh, BPMT, DMLT, MSc, PhD.
  • Good Clinical Laboratory Practices (GCLP) Certificate Course is conducted every year since 2005 for training laboratory personnel, all over the Mumbai and surrounding areas.
  • Summer Training: Undergraduate students from basic sciences all over Mumbai participate in summer training in CCBL.
  • Despite so many courses being run, the department is involved in conducting ‘Shidori’ for First and Second MBBS Students and helping the students in the publication of ‘Drishti’ magazine.

2. Research:

Ongoing Projects:

  1. Biochemical parameters in HIV-TB coinfection
  2. Characterization and assessment of anti-cancer activity of Indian honey
  3. Predictive values of biochemical markers in cardiovascular disorders and renal diseases
  4. Role of cardiac and inflammatory markers and their inter-relationships in cardiac disorders
  5. Validation of a point-of-care testing device and biochemical-hematological evaluations in renal diseases
  6. Reevaluation of liver enzymes: Healthy reference ranges and its modulating factors in large scale population studies

Collaboration with:

  1. IIT Bombay
  2. Haffkine Institute
  3. NIRRH
  4. TIFR

3. Patient Care:

Central Clinical Biochemistry Laboratory (CCBL):

Patients’ samples are analyzed on:

  • TWO new Olympus AU 680 Fully Automatic Biochemistry Analyzers
  • TWO Olympus AU 400 Fully Automatic Biochemistry Analyzers
  • ONE ErbaMannhein EM 200 Fully Automatic Biochemistry Analyzer along with
  • Thermofisher Scientific Spectronic 20D Spectrophotometer.

The biochemical parameters which are analyzed on routine basis are:

  • Blood Sugar (Fasting, Post Prandial & Random)
  • Serum Creatinine
  • Blood Urea Nitrogen
  • Serum Total Protein
  • Serum Albumin
  • Serum Alkaline Phosphatase
  • Serum Aspartate Transaminase
  • Serum Alanine Transaminase
  • Serum Uric acid
  • Serum Bilirubin (Direct & Indirect)
  • Serum Electrolytes (Na+, K+ & Cl-)
  • Serum Calcium
  • Serum Phosphorous
  • Urine Sugar
  • Urine Proteins

CCBL receives 800-1000 samples on which approximately 10000 tests are performed daily.

Emergency Medical Services Laboratory (EMS Lab):

Patients’ samples are analyzed for biochemical parameters on:

  • ONE Randox Rx Daytona Fully Automatic Biochemistry Analyzer
  • ONE ErbaMannhein EM 200 Fully Automatic Biochemistry Analyzer
  • ONE Transasia ERBA Easylyte Electrolyte Analyzer
  • ONE Roche Electrolyte Analyzer along with
  • Thermofisher Scientific Spectronic 20D Spectrophotometer.

The biochemical parameters which are analyzed daily are:

  • Blood Sugar (Fasting, Post Prandial & Random)
  • Serum Creatinine
  • Blood Urea Nitrogen
  • Serum Electrolytes (Na+, K+ & Cl-)
  • Serum Bilirubin (Direct & Indirect)
  • Serum Aspartate Transaminase (AST)
  • Serum Alanine Transaminase (ALT)
  • Urine Sugar

EMS Lab provide laboratory services 24x7x365 having a sample load of approximately 700-800 samples on which approximately 7000 tests are performed daily.

Facilities, Equipments & Special services

Laboratory facilities

U.G.- one(60 students)
P.G.- two(12,6 students)

Lecture Theatre :

  • U.G./P.G. – one(200 students)

Seminar Room:

  • One (25 seats)

For Student

Students on Roll

Undergraduate :

Ist MBBS 180
F.Y.O.T./P.T. 80
S.Y.P.T. 40

Postgraduate :

D.M.L.T M.Sc.Papers (Part I) 12
Biochemistry M.Sc.Papers (Part II) 12
Biochemistry M.Sc.(Research) 09 (existing) – 15 (Total sanctioned capacity)
Biochemistry Ph.D 04 (existing) – 5 (Total sanctioned capacity)

Courses Offered

The Department of Biochemistry offers the following courses :
  1. Diploma in Medical Laboratory Technology (DMLT)
  2. M. Sc.- By papers
  3. M. Sc.- By research
  4. Ph. D.- Science
  5. Summer Training (Observership) to undergraduate science students.
  6. Good Clinical Laboratory Practices course (GCLP)

The details are as follows :

  1. DMLT – Total no. of seats – 12 The applications are invited after the declaration of Mumbai University B.Sc. results. Students offering Biochemistry, Chemistry, Microbiology, Zoology and Botany are eligible to apply for this course. The applications are invited by Lokmanya Tilak Memorial Municipal Medical College (LTMMC) and Sion Hospital, Mumbai. Interviews are generally conducted after M. Sc.(by papers) and M. Sc.(by research) seats are filled up.
  2. M. Sc. (By papers) in Biochemistry & M. Sc (By research) Eligibility criterion for M. Sc. (By Papers) and M. Sc.(By Research) degree in Biochemistry As per University of Mumbai ordinance 0.2441 & 0.2445 a candidate having minimum 3 units in chemistry with any combination of units in biological sciences is eligible to apply for M. Sc. (By Papers) and M. Sc.(By research) degree in Biochemistry respectively.M. Sc (By research) : Seats – Subject to availability.University seats are filled by University of Mumbai. The forms are available with the University office, fort campus. The ten College seats are filled by applications invited by Seth G. S. Medical College, Parel, Mumbai for all the three Municipal Medical Colleges. One application form is to be filled with preference to be given as M. Sc. (by papers); M. Sc (by research) in Biochemistry as well as in Microbiology and Applied Biology courses. The preference among the three municipal medical colleges has also to be filled in by the applicants in this form. Applications are invited after the declaration of B.Sc. results by University of Mumbai. The interviews for M. Sc. (by research) are held after the third round for M. Sc.(by papers) is completed by University of Mumbai.
  3. 3) Ph.D. seats: Subject to availability.Eligibility criteria for Ph.D.(science) degree in Biochemistry:

Candidates with M. Sc.(By papers) or M. Sc.(By Research) in Biochemistry are eligible to apply for Ph.D. (Science) degree in Biochemistry.
Applications are invited after M. Sc. results of the University of Mumbai are declared. The application forms are available with Dean’s office, Seth G.S. Medical College, Parel, Mumbai. Interviews are conducted after displaying the merit list.

  • 4) Summer Training : Applications are made by F. Y., S. Y. or T.Y. students from Science faculty of basic science Colleges to Department of Biochemistry. An amount of Rs.150/- to be paid to Municipal Corporation of Greater Mumbai in the KEM Hospital. One month’s observership is available in the Central Clinical Biochemistry Laboratory (CCBL) to undergraduate B.Sc. students.
  • 5) “Good Clinical Laboratory Practices” (GCLP) Course.
    GCLP is conducted by the Department of Biochemistry, Seth G. S. Medical College, in October every year.The objectives of the course is to make the participants aware of :Changing health care scenario and role of clinical Laboratory Practices
    Appropriate quality control procedures and
    Bench marking for quality performance and appraisal of the clinical laboratory processes.
    Who can apply.
    a. B. Sc. with Chemistry / Zoology / Microbiology / Life sciences / Biochemistry / Biotechnology as principal subjects
    b. Laboratory Personnel with 2 years of experience, in the laboratory. c. H.S.C. with CMLT
    d. Candidates doing M. Sc. in any of the biological Sciences.Handwritten applications can be sent for registration for G.C.L.P. course in the month of September of any year at the following address:-Dr. S. P. Dandekar
    Course Director,
    Prof. & Head Department of Biochemistry Department,
    G. S. M. College & KEM Hospital,
    Parel,
    Mumbai – 400 012
    E mail.: suchetad@hotmail.com

For Patient

Other

Certificate course in Good Clinical Laboratory Practices

OnGoing Projects

 

Project 1 :
  • Biochemical alterations in alcoholics with hepatitis and steatosis Project of Ms.Sonal J.Sawant Ph.D student under my guidance
Project 2 :
  • Mutation analysis in beta thalassemia with reference to communicty distribution and prenatal diagnosis project of Mr.Flavian Vaz. Ph.D student under my guidance.
  • Detection of Dchenne Carriers by multifarious tests.
  • V.International congress on Neuromuscular diseases held at Marseilles, France, September, 1982.

Ongoing research projects :

  1. Study of some liver function tests in alcoholic HIV patients
  2. Column chromatographic separation of Cactor VIII from pooled plasma.
  3. Vitamin status in HIV/AIDS patients Guided M.Sc. thesis of Univ.of Mumbai.

Acute phase reactacts in infection and inflammation with special emphasis on B-hemolytic streptococcel infection

Location

Contact Detail

News & Updates

Poster:

Department of Biochemistry Poster-page-001

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