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Endocrinology



Background History

In 1959, Diabetes clinic was started by Dr. J C  Patel and Dr. M K Dhirwani (Hon. Asstt. Physician). In 1962, Endocrinology Clinic was started by Prof P. Raghavan and Dr. S D Bhandarkar (Hon. Asstt. Physician).  Dr. S D Bhandarkar also started looking after the Thyroid clinic which was initiated by Dr. Satoskar.  In 1971, 12 indoor beds were allotted for diabetes and endocrinology services.
In 1973, Dr. Bhandarkar was given charge of both the Endocrinology and Diabetes clinics after the untimely demise of Dr. Dhirwani. In 1979, the Diabetes and Endocrinology clinics were combined into one “Division of Endocrinology and Metabolic Disorders”.  In 1979, “Puberty and Growth Clinic” was added to the activities of the Department.  In 1980, the Division was given 12 more beds, making a total to 24 beds.  In 1981, the Division was recognized provisionally by the National Board of Examinations to enroll post-graduate students for MNAMS (Endocrinology). In 1983, the division was recognized by the University of Bombay to enroll students for DM (Endocrinology).  The Division of Endocrinology and Metabolic Disorders was re-designated as the Department of Endocrinology.  In 1989 radioimmuno hormone assay laboratory was started with the financial support of the Bai Vijkorbai Mayaram Khakhar Foundtion Trust.

In 1991, Dr. Padma S Menon took over the department as Prof. and Head of Department. Under her guidance, not only patient care, also the post graduate training and clinical data capturing improved over time. She upgraded the lab machinery to automated chemiluminescent assays. Pituitary tumor management was streamlined, by regular meetings with neurosurgeons. Research (academic/drug) trial set up was established. In 2001 DXA scanner for bone mineral density measurement was installed.
In 2004, Dr. Nalini S Shah took over the department as Prof. and Head of Department. Pediatric Endocrinology services were added and we have pan India referrals for pediatric endocrine disorders. Our department is unique, where both pediatric and adult endocrinology is catered too. In 2007 DM (Endocrinology) course got MCI recognition.  In 2007 Molecular endocrinology laboratory was established for conducting research on genetic aspects of Endocrine disorders. For these research projects department has been awarded DBT/DST grants. She further upgraded the lab machinery by adding fully automated high output chemiluminescene machine, and HbA1c Analyzer.  Patient care and post graduate training was furthered with interdepartmental meeting (Adrenal, Pituitary, Thyroid, DSD, and H&N), inter-hospital endocrine meets (local/national). Our original research work publications (n= 140), have given internationally  recognition to the department. As the result of which department was chosen as the first international center by the US Endocrine Society, for Ambassador Exchange programmein 2013.
In the year 2018 after Dr Nalini Shah retired, Dr Tushar Bandgar took over as the head of the department. Under his auspices a specialised endocrine-oncology opd was set up in the year 2019 followed by the diabetes foot clinic, obesity clinic and adrenal disorders clinic in the year 2020. He also instituted the Endocrine-Oncology fellowship programme in the year 2021. The department hosted the international conference Endo-Update 2022 and invited eminent international speakers, the conference received an overwhelming response from delegates all over India and was a huge success. Numerous national and international research papers have been published by his students over the past few years (>200). Apart from guiding his students to achieve academic excellence he has also played an instrumental role in upgrading the lab machinery (Immunoassay machine Advia Centaur CP immunoassay and HbA1c machine)

Under his leadership the department strives to achieve greater heights and will continue to do so in the years to come.


Staff

Teaching Staff:

Sr No

Name

Designation

Teaching Experience

1

Dr.Tushar Bandgar

Professor & Head

17 Years

2

Dr.Anurag Lila

Additional Professor

12 Years

3

Dr. irendra Patil

Associate Professor

5 Years

4

Dr. Saba Memon

Assistant Professor

2 Years

5

Dr. Manjiri Karlekar

Assistant Professor

2 Years


Residents:


Name of the Resident

Designation

Dr. Manjunath HD

Bonded Assistant Professor

Dr. Rohit Barnabas

Bonded Assistant Professor

Dr. Sandeep Kumar

Bonded Assistant Professor

Dr. Aditya Phadte

3Rd Year DM resident

Dr. Chethan Y

3Rd Year DM resident

Dr. Anima Sharma

3Rd Year DM resident

Dr Divya Ragate

2nd Year DM Resident

Dr Ketki Ambulkar

2nd Year DM Resident

Dr Aaditya Daga

1st Year DM Resident

Dr Anuj Ban

1st Year DM Resident

Dr Archana Rao

1st Year DM Resident

Dr Anand Zhope

2nd Year DD

Dr Yahya Khan

1st Year DD

Dr Tausif Manihar

House Officer


Non-Teaching staff:-


Sr No

Name

Designation

1

Mr Pradeep Surve

Senior Biochemist

2

Mrs. Priyanka p Patil

Lab Technician

3

Ms. Deepa Nachankar

Dietician

4

Ms.Pooja Dabholkar

Lab Technician

5

Mrs. Siddhi Raut

Lab Assistant

6

Mr Pravin Surve

Brother

7

Mrs. Priyanka Gavas

RA

8

Mr. Bhavesh Dhaware

Lab Servent

9

Mr. Hukumchand Goyal

Lab Servent

10

Mrs. Geeta Padaya

OPD Servent

11

Mr. Kiran Mehra

OPD Servent

12

Mrs. Alka Pawar

OPD Servent


Research Staff:-

Sr No

Name

Designation

1

Dr. Vyankatesh Shivne

Co-Investigator & Clinical research associate

2

Dr. Neelam Jaguste

Sr. CRC & QA officer

3

Mr. Prasad Adivarekar

Data Entry Operator

4

Mrs. Rashmi Iswalkar

Clerical Help

5

Mrs. Nandini Todankar

Technical Help II

6

MS. Shrutika Vilankar

Cherical Help

7

Ms. Samiksha Hegiste

Research Assistant

8

Ms. Amruta Jakate

CRC

9

Ms. Prerna Vishe

CRC

10

Ms. Kajal Ovhal

CRC

11

Ms. Mayuri Jondhale

CRC

12

Ms. Ashwini Kamble

CRC

13

Ms. Shubhangi Wagh

CRC

14

Ms. Nikita Chavan

Lab Technician

15

Mr Shubham Pujari

Lab Technician

16

Mr. Sarthank Karshingkar

Technical Help III

The department has an attached Hormone Assay Laboratory where following machine are available
Fully Automated Chemiluminescence Machines- 2
Fully Automated Biochemistry Autoanalyzer- 1
HbA1c analyzer by HPLC method- 1
Following tests are routinely performed in Hormone Assay Lab

  • T3, T4, TSH
  • FBS and PLBS
  • HbA1c
  • AMA
  • LH
  • FSH
  • Prolactin
  • Testosterone
  • Cortisol
  • PG Growth Hormone
  • ACTH
  • PTH
  • IGF 1
  • IGF BP3

Other Facilities:

  • Molecular Endocrine Laboratory for research purpose to assess genotype phenotype correlation of various endocrine disorders
  • Bone Mineral Densitometry ( DXA Scan)

DM (Endocrinology) Course:
There are three registrations (seats) available per year for DM Endocrinology course. This course has been recognized by Medical Council of India (MCI). The process of application/ appointment is common as mentioned under specialty registrations.
In October 2015 recognized DM Endocrinology seats increased from 1 to 3.
Total Passed DM Students till 2022:- 68 Students
Diploma in Diabetes:
At present one seat per year is available for Diploma in Diabetes. The process of application/ appointment is common as mentioned under specialty registrations.
Total Passed DD Students till 2021:- 31 Students
PhD and MSc in Applied Biology:
Department is recognized by the university for PhD in Applied Biology. We enroll one student per year on availability. We also enroll MSc in Applied Biology students in our department.
Endocrine Oncology Fellowship:
Endocrine Oncology fellowship of 1 year duration Introduced in the year 2020.

Awards:-

Sr No

Award

Year

Name of the resident

1

First prize in poster presentation: EndoUpdate

2022

D Anima Sharma

 

MCGM Best Resident Award

2023

 

First prize in SAFES Inter-Nation Quiz

2023

2

Poster presentation 2nd prize
ESCICON

2022

Dr Chethan Y

 

Poster presentation 1st prize
ENDO UPDATE

2022

3

1st runner up in Poster presentation

ENDO UPDATE       

2022

Dr Divya Ragate

4

Yuvaratna award

2023

Dr Saba Memon

01 Unit ( Dr TRB)

2023:
1: Phadte A, Sarathi V, Budyal S, Lila A, Memon SS, Karlekar M, Patil V, Shah N,Bandgar T. Gonadotropin-Dependent Precocious Puberty: Single-Center Experience From Western India. Indian Pediatr. 2023 Jun 15;60(6):463-466. Epub 2023 Mar 20. PMID: 37211886.

2: Dodamani MH, Lila AR, Memon SS, Sarathi V, Arya S, Rane A, Sehemby MK, Garg R, Bhandare VV, Karlekar M, Patil VA, Kunwar A, Bandgar TR. Genotypic Spectrum and its Correlation with Alopecia and Clinical Response in Hereditary Vitamin D Resistant Rickets: Our Experience and Systematic Review. Calcif Tissue Int. 2023
Apr;112(4):483-492. doi: 10.1007/s00223-023-01061-8. Epub 2023 Jan 27. PMID: 36705686.

3: Sharma A, Patil V, Sarathi V, Purandare N, Hira P, Memon S, Jadhav SS, Karlekar M, Lila AR, Bandgar T. Dual-phase computed tomography for localization of parathyroid lesions in children and adolescents with primary hyperparathyroidism. Ann Endocrinol (Paris). 2023 Mar 10:S0003-4266(23)00035-5. doi: 0.1016/j.ando.2023.03.001. Epub ahead of print. PMID: 36906257.

4: Phadte A, Arya S, Sarathi V, Lila A, Maheshwari M, Memon SS, Rane A, Patil V, Rai K, Raghav D, Kunwar A, Bandgar T. Side-chain cleavage enzyme deficiency: Systematic review and case series. Clin Endocrinol (Oxf). 2023
Mar;98(3):351-362. doi: 10.1111/cen.14848. Epub 2022 Nov 17. PMID: 36357326.

5: Barnabas R, Jadhav S, Arya S, Lila AR, Sarathi V, Shah GR, Bhandare VV, Shah NS, Kunwar A, Bandgar T. Luteinizing hormone β-subunit deficiency: Report of a novel LHB likely pathogenic variant and a systematic review of the published literature. Clin Endocrinol (Oxf). 2023 Mar;98(3):383-393. doi:
10.1111/cen.14749. Epub 2022 May 4. PMID: 35470463.

6: Gosavi V, Lila A, Memon SS, Sarathi V, Goroshi M, Jamale T, Thakare S, Phadte A, Patil V, Bandgar T. Spectrum of renal dysfunction after curative parathyroidectomy in symptomatic primary hyperparathyroidism. Ann Endocrinol (Paris). 2023 Feb;84(1):14-20. doi: 10.1016/j.ando.2022.10.015. Epub 2022 Dec
20. PMID: 36563936.

7: Krishnappa B, Shah R, Memon SS, Diwaker C, Lila AR, Patil VA, Shah NS, Bandgar TR. Glucocorticoid therapy as first-line treatment in primary hypophysitis: a systematic review and individual patient data meta-analysis.
Endocr Connect. 2022 Dec 22;12(2):e220311. doi: 10.1530/EC-22-0311. PMID: 36445257; PMCID: PMC9874965.

8: Rathod K, Memon SS, Mahajan P, Lila A, Thakkar D, Deshmukh H, Bandgar T. Adrenal Venous Sampling in Primary Aldosteronism: Single-Centre Experience from Western India. Indian J Endocrinol Metab. 2023 Jan-Feb;27(1):80-86. doi:
10.4103/ijem.ijem_177_22. Epub 2022 Dec 20. PMID: 37215273; PMCID: PMC10198195.

2022:
1: Gosavi V, Lila A, Memon SS, Sarathi V, Goroshi M, Jamale T, Thakare S, Phadte A, Patil V, Bandgar T. Spectrum of renal dysfunction after curative parathyroidectomy in symptomatic primary hyperparathyroidism. Ann Endocrinol (Paris). 2023 Feb;84(1):14-20. doi: 10.1016/j.ando.2022.10.015. Epub 2022 Dec 20. PMID: 36563936.

2: Krishnappa B, Shah R, Memon SS, Diwaker C, Lila AR, Patil VA, Shah NS, Bandgar TR. Glucocorticoid therapy as first-line treatment in primary hypophysitis: a systematic review and individual patient data meta-analysis.
Endocr Connect. 2022 Dec 22;12(2):e220311. doi: 10.1530/EC-22-0311. PMID: 36445257; PMCID: PMC9874965.

3: Dodamani MH, Lila AR, Memon SS, Sarathi V, Arya S, Rane A, Sehemby MK, Garg R, Bhandare VV, Karlekar M, Patil VA, Kunwar A, Bandgar TR. Genotypic Spectrum and its Correlation with Alopecia and Clinical Response in Hereditary Vitamin D Resistant Rickets: Our Experience and Systematic Review. Calcif Tissue Int. 2023
Jan 27. doi: 10.1007/s00223-023-01061-8. Epub ahead of print. PMID: 36705686.

4: Side-Chain Cleavage Enzyme Deficiency: Systematic Review and Case Series. Phadte A, Arya S, Sarathi V, Lila A, Maheshwari M, Memon SS, Rane A, Patil V, Rai K, Raghav D, Kunwar A, Bandgar T. ClinEndocrinol (Oxf). 2022 Nov 10. doi: 10.1111/cen.14848. Epub ahead of print. PMID: 36357326.

5: Genetic spectrum of Kallmann syndrome: Single-center experience and systematic review. Patil VA, Lila AR, Shah N, Arya S, Sarathi V, Shah R, Jadhav SS, Memon SS, Karlekar M, Bandgar T. ClinEndocrinol (Oxf). 2022 Dec;97(6):804-813. doi: 10.1111/cen.14822. Epub 2022 Sep 30. PMID: 36138264.

6: Comparison of the Sensitivity of 68 Ga-DOTATATE PET/CT with Other Imaging Modalities in Detecting Head and Neck Paraganglioma: Experience from Western India. Dodamani MH, Jaiswal SK, Sarathi V, Marfatia H, D'Cruz A, Malhotra G, Hira P, Patil VA, Lila AR, Shah NS, BandgarTR.World J Nucl Med. 2022 Aug 16;21(3):184-191. doi: 10.1055/s-0042-1751030. PMID: 36060084; PMCID: PMC9436509.

7: 17β hydroxysteroid dehydrogenase 3 deficiency in 46,XY disorders of sex development: Our experience and a gender role-focused systematic review.
Krishnappa B, Arya S, Lila AR, Sarathi V, Memon SS, Barnabas R, Kumbhar BV, Bhandare VV, Patil V, Shah NS, Kunwar A, Bandgar T. ClinEndocrinol (Oxf). 2022 Jul;97(1):43-51. doi: 10.1111/cen.14694. Epub 2022 Feb 27. PMID: 35170787.

8: Giant prolactinoma in children and adolescents: a single-center experience and systematic review.
Kumar S, Sarathi V, Lila AR, Sehemby M, Memon SS, Karlekar M, Sankhe S, Patil VA, Shah N, Bandgar T. Pituitary. 2022 Jul 18. doi: 10.1007/s11102-022-01250-y. Epub ahead of print. PMID: 35851929.

9: Luteinizing hormone β-subunit deficiency: Report of a novel LHB likely pathogenic variant and a systematic review of the published literature.
Barnabas R, Jadhav S, Arya S, Lila AR, Sarathi V, Shah GR, Bhandare VV, Shah NS, Kunwar A, Bandgar T. ClinEndocrinol (Oxf). 2022 Apr 25. doi: 10.1111/cen.14749. Epub ahead of print. PMID: 35470463.

10: Genotype-Phenotype Correlations in Asian Indian Children and Adolescents with Primary Hyperparathyroidism
Sharma A, Memon S, Lila AR, Sarathi V, Arya S, Jadhav SS, Hira P, Garale M, Gosavi V, Karlekar M, Patil V, BandgarT..Calcif Tissue Int. 2022 May 14. doi: 10.1007/s00223-022-00985-x. Epub ahead of print. PMID: 35567607.

11: Gonadal dysfunction in male patients with Budd Chiari syndrome and its reversibility with treatment.
Ramani N, Kawli K, Karad A, Kale A, Kahalekar V, Sundaram S, Bhatia S, Shah R, Bandgar T, Deshmukh H, Patwardhan S, Shukla A. Hepatol Int. 2022 Jun;16(3):640-648. doi: 10.1007/s12072-022-10316-9. Epub 2022 Mar 17. PMID: 35301679.

12: Clinical Spectrum of Adrenal Cushing's Syndrome and the Caution for Interpretation of Adrenocorticotrophic Hormone: A Single-Center Experience
Gosavi V, Lila A, Memon SS, Sarathi V, Thakkar K, Dalvi A, Malhotra G, Prakash G, Patil V, Shah NS, BandgarT..HormMetab Res. 2022 Feb;54(2):57-66. doi: 10.1055/a-1735-3232. Epub 2022 Feb 7. PMID: 35130566.

13: 17α-Hydroxylase/17,20-Lyase Deficiency in 46,XY: Our Experience and Review of Literature.
Maheshwari M, Arya S, Lila AR, Sarathi V, Barnabas R, Rai K, Bhandare VV, Memon SS, Karlekar MP, Patil V, Shah NS, Kunwar A, Bandgar T. J Endocr Soc. 2022 Jan 29;6(3):bvac011. doi: 10.1210/jendso/bvac011. PMID: 35178494; PMCID: PMC8845120.

14: Pituitary stalk interruption syndrome: phenotype, predictors, and pathophysiology of perinatal events.
Diwaker C, Thadani P, Memon SS, Sarathi V, Lila AR, Arya S, Krishnappa B, Karlekar M, Patil VA, Shah N, Bandgar T. Pituitary. 2022 Aug;25(4):645-652. doi: 10.1007/s11102-022-01243-x. Epub 2022 Jun 24. PMID: 35749012.

15: Percentage arterial enhancement on 2D CT in the diagnosis of primary hyperparathyroidism: A prospective validation study and potential pitfalls.
Sonawane S, Jadhav SS, Goroshi M, Krishnappa B, Sharma A, Hira P, Garle MN, Gosavi V, Memon S, Patil VA, Lila AR, Shah N, Bandgar T. Head Neck. 2022 Aug;44(8):1849-1856. doi: 10.1002/hed.27108. Epub 2022 May 31. PMID: 35638259.

16: Effects of a Lifestyle Intervention to Prevent Deterioration in Glycemic Status Among South Asian Women With Recent Gestational Diabetes: A Randomized Clinical Trial
Tandon N, Gupta Y, Kapoor D, Lakshmi JK, Praveen D, Bhattacharya A, Billot L, Naheed A, de Silva A, Gupta I, Farzana N, John R, Ajanthan S, Divakar H, Bhatla N, Desai A, Pathmeswaran A, Prabhakaran D, Joshi R, Jan S, Teede H, Zoungas S, Patel A; LIVING Collaborative Group.. JAMA Netw Open. 2022 Mar 1;5(3):e220773. doi: 10.1001/jamanetworkopen.2022.0773. PMID: 35234881; PMCID: PMC8892226.

17: Regional genotypic variations in normosmic congenital hypogonadotropichypogonadism: our experience and systematic review
Patil VA, Lila AR, Shah N, Arya S, Ekbote AV, Sarathi V, Shah R, Jadhav SS, Memon SS, BandgarT.. Pituitary. 2022 Jun;25(3):444-453. doi: 10.1007/s11102-022-01209-z. Epub 2022 Feb 8. PMID: 35133534.

18:GNRH1 Variants in Congenital Hypogonadotropic Hypogonadism: Single-Center Experience and Systematic Literature
Patil VA, Lila AR, Shah N, Ekbote AV, Shah R, Bhandare VV, Sarathi V, Arya S, Memon SS, Kunwar A, Bandgar T.  Review. Neuroendocrinology. 2022;112(8):723-732. doi: 10.1159/000521558. Epub 2021 Dec 17. PMID: 34923491.

National Publications:
1: Role of Preoperative Blockade in Pheochromocytoma-Paraganglioma: A Clinician's Perspective.
Karlekar MP, Memon SS, Bandgar TR. Indian J EndocrinolMetab. 2022 Jan-Feb;26(1):30-31. doi: 10.4103/2230-8210.343877. Epub 2022 Apr 27. PMID: 35662759; PMCID: PMC9162254.

2: The Utility of 68Ga-DOTATATE PET/CT in Localizing Primary/Metastatic Pheochromocytoma and Paraganglioma: Asian Indian Experience
Jaiswal SK, Sarathi V, Malhotra G, Verma P, Hira P, Badhe P, Memon SS, Barnabas R, Patil VA, Anurag, Lila R, Shah NS, BandgarT.. Indian J EndocrinolMetab. 2021 Sep-Oct;25(5):410-417. doi: 10.4103/ijem.ijem_307_21. Epub 2022 Jan 12. PMID: 35300451; PMCID: PMC8923324.

2021:
International Publications:

1: Octreotide-LAR is a Useful Alternative for the Management of Diazoxide- Responsive Congenital Hyperinsulinism.
Karlekar MP, Sarathi V, Arya S, Flanagan SE, Patil V, Lila A, Shah N, Bandgar T. HormMetab Res. 2021 Nov;53(11):723-729. doi: 10.1055/a-1654-8542. Epub 2021 Nov 5. PMID: 34740273.

2: Exonic WT1 pathogenic variants in 46,XY DSD associated with  gonadoblastoma.
Arya S, Kumar S, Lila AR, Sarathi V, Memon SS, Barnabas R, Thakkar H, Patil VA, Shah NS, Bandgar TR. Endocr Connect. 2021 Nov 25;10(12):1522-1530. doi:10.1530/EC-21-0289. PMID: 34727091.

3: Metastatic cluster 2-related pheochromocytoma/paraganglioma: a single-center experience and systematic review.
Kumar S, Lila AR, Memon SS, Sarathi V, Patil VA, Menon S, Mittal N, Prakash G, Malhotra G, Shah NS, Bandgar TR. Endocr Connect. 2021 Nov 11;10(11):1463-1476. doi: 10.1530/EC-21-0455. PMID: 34662294; PMCID: PMC8630763.

4: Low-Dose, Low-Specific Activity 131I-metaiodobenzyl Guanidine Therapy in Metastatic Pheochromocytoma/Sympathetic Paraganglioma: Single-Center Experience from Western India.
Barnabas R, Jaiswal SK, Memon SS, Sarathi V, Malhotra G, Verma P, Patil VA, Lila AR, Shah NS, Bandgar TR. Indian J EndocrinolMetab. 2021 Mar-Apr;25(2):148-159. doi:10.4103/ijem.IJEM_52_21. Epub 2021 Sep 8. PMID: 34660244; PMCID: PMC8477742.

5: Prevalence of primary aldosteronism in type 2 diabetes mellitus and hypertension: A prospective study from Western India
Memon SS, Lila A, Barnabas R, Goroshi M, Sarathi V, Shivane V, Patil V, Shah N, BandgarT..ClinEndocrinol (Oxf). 2021 Sep 27. doi: 10.1111/cen.14598. Epub ahead of print. PMID: 34580897. 

6: 68Ga-DOTATATE PET/CT imaging in endogenous hyperinsulinemic hypoglycemia: A tertiary endocrine centre experience.
Shah R, Sehemby M, Garg R, Purandare N, Hira P, Mahajan A, Lele V, Malhotra G, Verma P, Rojekar A, Dalvi A, Uchino S, Rastogi S, Lila A, Patil V, Shah N, Bandgar T. Clinic Endocrinol (Oxf). 2021 Sep 8. doi: 10.1111/cen.14586. Epub ahead of print. PMID: 34498757.

7: Genotype and phenotypic spectrum of vitamin D dependent rickets type 1A: our experience and systematic review
Dodamani MH, Sehemby M, Memon SS, Sarathi V, Lila AR, Chapla A, Bhandare VV, Patil VA, Shah NS, Thomas N, Kunwar A, BandgarTR.. J PediatrEndocrinolMetab. 2021 Sep 8;34(12):1505-1513. doi:10.1515/jpem-2021-0403. PMID: 34492747.

8: Clinical, Hormonal, Genetic, and Molecular Characteristics in Androgen Insensitivity Syndrome in an Asian Indian Cohort from a Single Centre in Western India
Arya S, Barnabas R, Lila AR, Sarathi V, Memon SS, Bhandare VV, Thakkar K, Patil V, Shah NS, Kunwar A, BandgarT.. Sex Dev. 2021;15(4):253-261. doi: 10.1159/000517763. Epub 2021 Jul 30. PMID: 34333495.

09: Gonadotropins for testicular descent in cryptorchid congenital hypogonadotropichypogonadism males beyond infancy
Sharma S, Shah R, Patil V, Lila AR, Sarathi V, Shah N, BandgarT.. J PediatrEndocrinolMetab. 2021 Apr 26;34(7):917-924. doi: 10.1515/jpem-2020-0683. PMID: 33894111.

10: Prostate-Specific Membrane Antigen Expression in Patients With Differentiated Thyroid Cancer With Thyroglobulin Elevation and Negative Iodine  Scintigraphy Using 68Ga-PSMA-HBED-CC PET/CT
Verma P, Malhotra G, Meshram V, Chandak A, Sonavane S, Lila AR, Bandgar TR, AsopaRV..ClinNucl Med. 2021 Aug 1;46(8):e406-e409. doi: 10.1097/RLU.0000000000003655. PMID: 33883490.

11: Preoperative Amlodipine Is Efficacious in Preventing Intraoperative HDI in Pheochromocytoma: Pilot RCT. Jaiswal SK, Memon SS, Lila A, Sarathi V, Goroshi M, Garg R, Barnabas R, Hemantkumar I, Patel RD, Oak S, Dalvi A, Garale M, Patil V, Shah NS, Bandgar T. J ClinEndocrinolMetab. 2021 Jul 13;106(8):e2907-e2918. doi: 10.1210/clinem/dgab231. PMID: 33839787.

12: Preoperative prediction of parathyroid carcinoma in an Asian Indian cohort
Shah R, Gosavi V, Mahajan A, Sonawane S, Hira P, Kurki V, Bal M, Sathe P, Pai P, D'Cruz A, Uchino S, Garale MN, Patil V, Lila A, Shah N, BandgarT.. Head Neck. 2021 Jul;43(7):2069-2080. doi: 10.1002/hed.26677. Epub 2021 Mar 10. PMID:33751728.

13: Early Pulse Glucocorticoid Therapy and Improved Hormonal Outcomes in Primary Hypophysitis. Krishnappa B, Shah R, Sarathi V, Lila AR, Sehemby MK, Patil VA, Sankhe S, Shah N, Bandgar T. Neuroendocrinology. 2021 Mar 19. doi: 10.1159/000516006. Epub ahead of print. PMID: 33744880.

14: POU1F1 mutations in combined pituitary hormone deficiency: differing spectrum of mutations in a Western-Indian cohort and systematic analysis of world literature.
Jadhav S, Diwaker C, Lila AR, Gada JV, Kale S, Sarathi V, Thadani PM, Arya S, Patil VA, Shah NS, Bandgar TR. Pituitary. 2021 Oct;24(5):657-669. doi:10.1007/s11102-021-01140-9. Epub 2021 Mar 20. PMID: 33742319.

15: Hereditary medullary thyroid carcinoma syndromes: experience from western India
Diwaker C, Sarathi V, Jaiswal SK, Shah R, Deshmukh A, Thomas AE, Prakash G, Malhotra G, Patil V, Lila A, Shah N, BandgarT.. Fam Cancer. 2021 Jul;20(3):241-251. doi: 10.1007/s10689-020-00219-9. Epub 2021 Jan 4. PMID:33392850.

16: Exendin-4-based imaging in insulinoma localization: Systematic review and meta-analysis.
Shah R, Garg R, Majmundar M, Purandare N, Malhotra G, Patil V, Ramteke- Jadhav S, Lila A, Shah N, Bandgar T. ClinEndocrinol (Oxf). 2021 Aug;95(2):354-364. doi: 10.1111/cen.14406. Epub 2021 Jan 21. PMID: 33386617

2020:
International Publications:

1.Cabergoline may act as a radioprotective agent in Cushing's disease.
Thakkar K, Lila A, Sarathi V, Ramteke-Jadhav S, Goroshi M, Memon SS, Krishnatry R, Gupta T, Jalali R, Goel A, Shah A, Sankhe S, Patil V, Bandgar T, Shah N S.ClinEndocrinol (Oxf). 2020 Jan;92(1):55-62. doi: 10.1111/cen.14123. Epub 2019 Nov 22.PMID: 31698511

2.Sellar surprises: a single-centre experience of unusual sellar masses.
Thakkar K, Ramteke-Jadhav S, Kasaliwal R, Memon SS, Patil V, Thadani P, Lomte N, Sankhe S, Goel A, Epari S, Goel N, Lila A, Shah NS, BandgarT.Endocr Connect. 2020 Feb;9(2):111-121. doi: 10.1530/EC-19-0497.PMID: 31910151

3.177Lu-DOTATATE therapy in metastatic/inoperable pheochromocytoma-paraganglioma.
Jaiswal SK, Sarathi V, Memon SS, Garg R, Malhotra G, Verma P, Shah R, Sehemby MK, Patil VA, Jadhav S, Lila AR, Shah NS, BandgarTR.Endocr Connect. 2020 Oct;9(9):864-873. doi: 10.1530/EC-20-0292.PMID: 32784267

4.Predictors of Chronic LH-Testosterone Axis Suppression in Male MacroprolactinomasWithNormoprolactinemia on Cabergoline.
Sehemby M, Lila AR, Sarathi V, Shah R, Sankhe S, Jaiswal SK, Ramteke-Jadhav S, Patil V, Shah N, Bandgar T.J ClinEndocrinolMetab. 2020 Dec 1;105(12):dgaa650. doi: 10.1210/clinem/dgaa650.PMID: 32942295

5.Exendin-4-based imaging in endogenous hyperinsulinemichypoglycaemia cohort: A tertiary Endocrine centre experience.
Garg R, Shah R, Tiwari A, Purandare N, Lele VR, Malhotra G, Verma P, Gosavi V, Dalvi A, Kumar Jaiswal S, Patil V, Ramteke-Jadhav S, Lila A, Shah N, BandgarT.ClinEndocrinol (Oxf). 2020 Dec;93(6):678-686. doi: 10.1111/cen.14299. Epub 2020 Aug 6.PMID: 32716527

6.Expanding genetic spectrum and discriminatory role of steroid profiling by LC-MS/MS in 11β-hydroxylase deficiency.
Karlekar MP, Sarathi V, Lila A, Rai K, Arya S, Bhandare VV, Atluri S, Patil V, Ramteke-Jadhav S, Shah NS, Kunwar A, BandgarT.ClinEndocrinol (Oxf). 2020 Dec 4. doi: 10.1111/cen.14376. Online ahead of print.PMID: 33275286

7.Management of Insulin Autoimmune Hypoglycaemia: Single-centre experience from Western India with systematic review of world literature.
Patel M, Shah R, Ramteke-Jadhav S, Patil V, Patel SK, Lila A, Shah N, BandgarT.ClinEndocrinol (Oxf). 2020 May;92(5):409-420. doi: 10.1111/cen.14174. Epub 2020 Feb 26.PMID: 32064669

8.Homozygous p.Val89Leu plays an important pathogenic role in 5α-reductase type 2 deficiency patients with homozygous p.Arg246Gln in SRD5A2.
Arya S, Tiwari A, Lila AR, Sarathi V, Bhandare VV, Kumbhar BV, Rai K, Kunwar A, Thakkar H, Thakkar K, Memon SS, Patil V, Khadilkar K, Jadhav SS, Shah NS, BandgarT.Eur J Endocrinol. 2020 Sep;183(3):275-284. doi: 10.1530/EJE-19-1050.PMID: 32567554

09.Prior testosterone replacement therapy may impact spermatogenic response to combined gonadotropin therapy in severe congenital hypogonadotropichypogonadism.
Shah R, Patil V, Sarathi V, Lila AR, Zacharin M, Krishnappa B, Sehemby M, Jaiswal SK, Jadhav PL, Ramteke-Jadhav S, Shah N, BandgarT.Pituitary. 2020 Nov 23. doi: 10.1007/s11102-020-01111-6. Online ahead of print.PMID: 33226541

10.The utility of 68Ga-DOTATATE PET/CT in localizing primary/metastatic pheochromocytoma and paraganglioma in children and adolescents - a single-center experience.
Jaiswal SK, Sarathi V, Malhotra G, Hira P, Shah R, Patil VA, Dalvi A, Prakash G, Lila AR, Shah NS, Bandgar T.J PediatrEndocrinolMetab. 2020 Nov 12:/j/jpem.ahead-of-print/jpem-2020-0354/jpem-2020-0354.xml. doi: 10.1515/jpem-2020-0354. Online ahead of print.PMID: 33180042

11.Comparison of 68Ga-DOTA-NaI3-Octreotide/tyr3-octreotate positron emission tomography/computed tomography and contrast-enhanced computed tomography in localization of tumors in multiple endocrine neoplasia 1 syndrome.
Patil VA, Goroshi MR, Shah H, Malhotra G, Hira P, Sarathi V, Lele VR, Jadhav S, Lila A, Bandgar TR, Shah NS.World J Nucl Med. 2020 Jan 29;19(2):99-105. doi: 10.4103/wjnm.WJNM_24_19. eCollection 2020 Apr-Jun.PMID: 32939195

12.Genetic spectrum and predictors of mutations in four known genes in Asian Indian patients with growth hormone deficiency and orthotopic posterior pituitary: an emphasis on regional genetic diversity.
Kale S, Gada JV, Jadhav S, Lila AR, Sarathi V, Budyal S, Patt H, Goroshi MR, Thadani PM, Arya S, Kamble AA, Patil VA, Acharya S, Sankhe S, Shivane V, Raghavan V, Bandgar TR, Shah NS.Pituitary. 2020 Dec;23(6):701-715. doi: 10.1007/s11102-020-01078-4.PMID: 32894409

13.Demographic and clinical profile of youth onset diabetes patients in India-Results from the baseline data of a clinic based registry of people with diabetes in India with young age at onset-[YDR-02].
16.Praveen PA, Madhu SV, Viswanathan M, Das S, Kakati S, Shah N, Chadha M, Bhadada SK, Kaur T, Dhaliwal RS, Das AK, Yajnik CS, TandonN.Pediatr Diabetes. 2019 Dec 29. doi: 10.1111/pedi.12973. Online ahead of print.

2019
1.Sympathetic paraganglioma: a single-center experience from western India
Jaiswal SK, Sarathi V, Memon SS, et al.. EndocrPract. 2019;25(3):211-219. doi:10.4158/EP-2018-0480

2.Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
Husain M, Birkenfeld AL, Donsmark M, et al.. N Engl J Med. 2019;381(9):841-851. doi:10.1056/NEJMoa1901118

3. Radiological differentiation of phaeochromocytoma from other malignant adrenal masses: importance of wash-in characteristics on multiphase CECT.
Goroshi M, Jadhav SS, Sarathi V, et al. Endocr Connect. 2019;8(7):898-905. doi:10.1530/EC-19-0198

4. Tumor induced osteomalacia in head and neck region: single center experience and systematic review
Shah R, Lila AR, Jadhav RS, et al. Endocr Connect. 2019;8(10):1330-1353. doi:10.1530/EC-19-0341

5. Primary pigmented nodular adrenocortical disease (PPNAD): single centre experience
Memon SS, Thakkar K, Patil V, et al. J PediatrEndocrinolMetab. 2019;32(4):391-397. doi:10.1515/jpem-2018-0413

6. Demographic and clinical profile of youth onset diabetes patients in India-Results from the baseline data of a clinic based registry of people with diabetes in India with young age at onset-[YDR-02]
Praveen PA, Madhu SV, Viswanathan M, et al. [published online ahead of print, 2019 Dec 29]. Pediatr Diabetes. 2019;10.1111/pedi.12973. doi:10.1111/pedi.12973

7. Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study.
McClung MR, O'Donoghue ML, Papapoulos SE, et al. Lancet Diabetes Endocrinol. 2019;7(12):899-911. doi:10.1016/S2213-8587(19)30346-8

8. Dose-Constraint Model to Predict Neuroendocrine Dysfunction in Young Patients With Brain Tumors: Data From a Prospective Study
Jalali R, Maitre M, Gupta T, et al.. PractRadiatOncol. 2019;9(4):e362-e371. doi:10.1016/j.prro.2019.02.011

9. Neumann HPH, Tsoy U, Bancos I, Amodru V, Walz MK, Tirosh A, Kaur RJ, McKenzie T, Qi X, Bandgar T, Petrov R, Yukina MY, Roslyakova A, van der Horst-Schrivers ANA, Berends AMA, Hoff AO, Castroneves LA, Ferrara AM, Rizzati S, Mian C, Dvorakova S, Hasse-Lazar K, Kvachenyuk A, Peczkowska M, Loli P, Erenler F, Krauss T, Almeida MQ, Liu L, Zhu F, Recasens M, Wohllk N, Corssmit EPM, Shafigullina Z, Calissendorff J, Grozinsky-Glasberg S, Kunavisarut T, Schalin-Jäntti C, Castinetti F, Vlcek P, Beltsevich D, Egorov VI, Schiavi F, Links TP, Lechan RM, Bausch B, Young WF Jr, Eng C; International Bilateral-Pheochromocytoma-Registry Group. Comparison of Pheochromocytoma-Specific Morbidity and Mortality Among Adults With Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy. JAMA Netw Open. 2019 Aug 2;2(8):e198898. doi: 10.1001/jamanetworkopen.2019.8898. PMID: 31397861; PMCID: PMC6692838.

10. Castinetti F, Waguespack SG, Machens A, Uchino S, Hasse-Lazar K, Sanso G, Else T, Dvorakova S, Qi XP, Elisei R, Maia AL, Glod J, Lourenço DM Jr, Valdes N, Mathiesen J, Wohllk N, Bandgar TR, Drui D, Korbonits M, Druce MR, Brain C, Kurzawinski T, Patocs A, Bugalho MJ, Lacroix A, Caron P, Fainstein-Day P, BorsonChazot F, Klein M, Links TP, Letizia C, Fugazzola L, Chabre O, Canu L, Cohen R, Tabarin A, SpeharUroic A, Maiter D, Laboureau S, Mian C, Peczkowska M, Sebag F, Brue T, Mirebeau-Prunier D, Leclerc L, Bausch B, Berdelou A, Sukurai A, Vlcek P, Krajewska J, Barontini M, Vaz Ferreira Vargas C, Valerio L, Ceolin L, Akshintala S, Hoff A, Godballe C, Jarzab B, Jimenez C, Eng C, Imai T, Schlumberger M, Grubbs E, Dralle H, Neumann HP, Baudin E. Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study. Lancet Diabetes Endocrinol. 2019 Mar;7(3):213-220. doi: 10.1016/S2213-8587(18)30336-X. Epub 2019 Jan 16. Erratum in: Lancet Diabetes Endocrinol. 2019 Mar;7(3):e3. PMID: 30660595; PMCID: PMC8132299

Academic Studies:

Sr. No.

Project No.

Title

3

EC/OA-173/ 2018

Effectiveness of various diagnostic tests in Cushing Syndrome: A retrospective analysis.

4

EC/OA-175/2018

Range of salivary cortisol (morning and late-night), and Overnight dexamethasone suppressed serum and salivary cortisol in chronic renal failure patients.

5

EC/OA-68/2019
02 Aug 2019

Clinical, Biochemical and Radiological characteristics of patients with Growth Hormone Deficiency and combined pituitary hormone deficiency – A Retrospective analysis.

6

EC/OA-94/2019

A prospective observational cohort study to identify the utility of risk-based screening strategy for long term complications in adolescent and adult cancer survivors of leukaemia and lymphoma

7

EC/OA-41/2021

Next-generation sequencing in Pheochromocytoma – Paraganglioma: single centre experience from Western India.

8

EC/OA-64/2021

Adrenocortical carcinoma in children and adolescents: Retrospective analysis

9

EC/OA-129/2021

Genotype-phenotype correlation in hypophosphatemic rickets: single center experience from western India

10

EC/OA-139/2021

Dysglycaemia in patients with previously diagnosed Gestational diabetes mellitus by IADPSG criteria Analysis of Data

11

EC/OA-195/ 2021

Pediatric Cushing’s disease- Single center experience from western India

12

EC/OA-200/ 2021

Pediatric Ectopic ACTH Syndrome Case series and review of literature

13

EC/OA-89/2022

A Nuclear Magnetic Resonance-Artificial Intelligence (NMR-AI) based Hybrid Approach for Modelling the Progression of Type 2 Diabetes Mellitus (T2DM)

14

EC/OA-90/2022

Evaluation and management of patients with Pituitary apoplexy: A retrospective study

15

EC/OA-91/2022

Pancreatic Neuroendocrine Tumors: Experience from a single tertiary center in India

16

EC/OA-130/2022

TSH secreting pituitary adenoma- Experience from a tertiary care centre

17

EC/OA-149/2022

Functional gonadotroph pituitary adenoma- Experience from a tertiary care center

18

EC/OA-171/2022

Tumour Induced Osteomalacia

19

EC/OA-184/2022

Biochemical characteristics in patients with genetically proven Disorders of Sexual Development/Differentiation (DSD)

20

EC/OA-13/2022

Retrospective analysis of 46, XY DSD patients with NR5A1pathogenic variants: a single-centre experience

21

EC/OA-16/2022

Primary adrenal insufficiency in children and adolescents of non 21 α hydroxylase deficiency etiology : A single centre  experience

22

EC/OA-17/2022

Primary Bilateral Macronodular adrenal hyperplasia : A Single Center Experience

23

EC/OA-18/2022

A retrospective analysis and comparison of the clinical, hormonal, radiological features and management outcomes of cases of primary and secondary hypophysitis

24

EC/OA-19/2022

Characterizing the spectrum of aldosterone-driver somatic mutations in India

25

EC/OA-22/2023

Multiple Endocrine Neoplasia Type 1 syndrome: A Single Center Experience

26

EC/OA-36/2023

Steroidogenic Acute Regulatory Proteinenzyme deficiency: A single centre experience and systematic review

27

EC/OA-65/2023

Treatment Strategies And Outcome Of Post-Operative Water And Electrolyte Imbalances In Patients With Sellar And Supra Sellar Mass: A Single-Centre Experience.

28

EC/OA-78/2023

The Retrospective analysis of macroprolactinoma: A single centre experience

29

EC/OA-106/2023

 

Pharma Studies:-

Sr. No.

Project No.

Title

1

EC / Pharma-02 / 2020

I8F-MC-GPGN(a)The Effect of Tirzepatide versus Dulaglutide on Major Adverse Cardiovascular Events in Patients with Type 2Diabetes(SURPASS-CVOT)

2

 EC/Pharma-10/2020

SIRO-CIPLA study (Inhaled Insulin): Randomized, Double-blind, Placebo-controlled, Multicenter, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of Prandial Technosphere® Insulin Inhalation Powder Versus Placebo Inhalation Powder in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Oral Antidiabetic Drugs Over a 24-week Treatment Period.

3

EC/PH - 07/2022

A research study to see how well the new weekly medicine IcoSema, which is a combination of insulin icodec and semaglutide, controls blood sugar level in people with type 2 diabetes compared to weekly insulin icodec (COMBINE 1). Trial ID: NN1535-4591

4

EC/PH - 08/2022

A Randomized, Controlled, Multicenter Study to Evaluate the Safety and Efficacy of Paltusotine in Subjects with Non-pharmacologically Treated Acromegaly.

5

   EC_Pharma_19_2022

Efficacy and safety of cagrilintide s.c. 2.4 mg in combination with semaglutide s.c. 2.4 mg (CagriSema s.c. 2.4 mg/2.4 mg) once weekly in participants with overweight or obesity and type 2 diabetes. NN9838-4609 (REDEFINE 2)

6

EC/Pharma_02/ 2023           

An Open-label, Single-arm, Multicenter Phase 4 Study to Evaluate Safety and Tolerability of Romosozumab(EVENITY®) in Postmenopausal Women in India with Osteoporosis and a High Risk of Fracture.(Protocol Number: 20210025)

Government Studies:


1.

EC/Govt_19_2007

ICMR study: Formation of   registry of people with diabetes in India with young age at onset. (Phase II)

2.

EC/OA-01/2021

A Randomized, Open label, pilot Study to Compare the Efficacy of Pioglitazone (7.5 mg) and  Pioglitazone (15 mg) on Glycemic Control in Patients with Type II Diabetes Mellitus who are not   controlled on either metformin (single drug) or both metformin and  DPP4 inhibitors/ sulfonylurea (2 drugs) or  metformin, sulfonylurea and DPP4 inhibitors (3 drugs)

3

EC/OA-89/2022
EC/Govt-05/2022

A Nuclear Magnetic Resonance-Artificial Intelligence (NMR-AI) based Hybrid Approach for Modelling the Progression of Type 2 Diabetes Mellitus (T2DM)

4

EC/Govt-4/2021

Study of maternally inherited mitochondrial DNA variants in women with Polycystic Ovarian Syndrome


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