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Hematology



J.C. Patel Department of Clinical Hematology

In 1961, Dr.J.C. Patel, Hon. Physician, Seth GS Medical College and KEM Hospital, obtained a grant of Rs.30, 000.00 from Glaxo Laboratories Ltd. to start work in Haematology.  A full-time medical officer and technician were appointed to work under the guidance of Dr. J.C. Patel and Prof.N.M. Purandare.  Over a period of six months, they established most of the laboratory tests necessary for diagnosis of various haematological disorder that were encountered in practice.
The department was named after Dr. J.C Patel in 1977. Medical Council of India (MCI) gave permission to super speciality course in start DM Clinical Haematology in 2001 and first batch of students got admission from 2002. Then MCI recognized DM course in 2012.
The department is located on 10th floor of multistorey building of this hospital and has dedicated state of art haematology day care centre on 11th floor, specialized haematology laboratory.  There is facility of clean and well-maintained ward with total capacity of 25 beds.  The day care facility has started to cater patients of Thalassemia, haemophilia and blood cancer such as leukaemia and lymphoma both in adults and paediatric patients.  It was inaugurated by honourable Dean and director, Dr. Avinash Supe in December 2016 and is funded by NATCO Trust.
The Dr. J. C. Patel Department of Haematology provides haematooncology services to the patients that are referred to the King Edward Memorial VII Hospital and caters to the lower strata of the society. This is one of the oldest and most prestigious Medical Colleges in India, with 1820 bed capacity & century old record of superlative patient care in all Departments. It has got one of the biggest Haematology Departments in Mumbai, with the monthly O.P.D. attendance of almost 350 to 500 patients coming from all over India.
The haematology department has easy access to the two main libraries,i.e., the central library of the hospital& the more specialized library of the IIH which is housed in the same building as the department. Besides these the department has its own collection of reference books.

Milestones –

Department started in 1961
DM Clinical Hematology course started in 2002
Dedicated Hematology Day care center started in 2015 with 10 beds and 5 reclining chairs with facility for day care chemotherapy, blood transfusion, regular blood transfusion and factor replacement therapy, rehabilitation therapy.

Section

J C Patel Hematology ward

Dedicated Hematology ward with 25 beds where blood cancer patients both adult and pediatric patients are admitted in this ward. Patients with hemophilia and thalassemia, other blood disorders patients are admitted in ward. There are 7 separate cabins for admission of blood cancer patients. In this ward we have dedicated medical social worker, psychologists and dedicate nutritionist.Here all types of blood cancer patients including acute leukemia, chronic leukemia and lymphoma are admitted

Hematology laboratory

There is dedicated lab on 10 th floor. Bone marrow examination is done for both adults and pediatrics. We usually do around 800 – 900 bone examinations in a year. Bone marrow reporting is done in the lab. We have a 5-part cell counter where all patients CBC done prior to chemotherapy. We have a fully automated coagulometer where coagulation tests are done. We have hemoglobin electrophoresis HPLC Machine where the diagnosis of thalassemia and sickle anemia diagnosis is done

Hematology day care center

Located on 11 th floor of the new MSB in KEM. 10 beds and 4 reclining chairs with seating arrangements for the patients and relatives with dedicated play area. There is dedicated rehabilitation area with all the equipment such as cycle, pulleys and CPM and others. Dedicated hemophilia multidisciplinary OPD conducted every Wednesday and CML OPD is conducted on every Wednesday morning in Hematology Day care. In day care chemotherapy, PICC line care and intrathecal chemotherapy procedures are done. Regular blood transfusion for thalassemia and supportive, chelation therapy. Round the clock services for the hemophilia patients.

We have more than 1300 Hemophilia patient registered with us and we also a International Hemophilia Training center where we conduct training programs for doctors, nurses, technicians in the care of Hemophilia. We do all types of surgeries in hemophilia including joint replacement and pseudotumor.

Facilities and procedure available in the department

  • Hemophilia comprehensive care.
  • Treatment of Hematolymphoid malignancies
    • Intravenous Chemotherapy
    • Intrathecal Chemotherapy
  • Thalassemia comprehensive care
  • Hemogram Retic count, ESR, HPLC
  • Bone marrow aspiration and biopsy
  • Bone marrow transplant
  • PT/APTT/Fibrinogen
  • Education and rehabilitations program for our patients
  • Procedure and tests done in Hematology dept
  • Bone marrow examination
  • PICC insertion and line care
  • Hemoglobin electrophoresis

Future outlook –

Bone marrow transplant tis the need of the hour in Mumbai for adults in public hospital. At present there is no BMT facility for adults with benign hematologic condition in any of the Public Hospital. We would like to have a dedicated BMT unit with 8 beds.

The department provides training for the residents registered for the following courses:

M.D. (Gen. Medicine) University of Bombay 3 year course
M.D. (Paediatrics) University of Bombay 3 year course
M.D. (Pathology) University of Bombay 3 year course

The Department is awaiting approval from the MCI for registering postgraduates for DM (Clinical Hematology) Thus for the term beginning in August 1999, the following registrations could be available.

  • DM [Clinical Hematology] University of Bombay 2 year course
  • 2 registrations could be available (open merit)

For details regarding application forms, selection criteria, please contact the post graduate section of the J.J. Hospital, Mumbai.

The following is the approximate distribution of the various postings during a two year residency DM [Clinical Hematology]

Hematology Wards [Junior resident]- 6 months
Laboratory Medicine Rotation- 6 months
Blood Bank Rotation- 3 months
BMT Rotation- 3 months
Hematology Wards [Senior resident]- 6 months

 

Working Schedule of Department

Out Patient Clinic Days Timings
New & Old Patients Monday & Thursday 9.00 to 3.00 pm

Indoor:

  • Department has 28 beds on indoor basis
  • On OPD basis daily 50 to 60 patients are seen in hematology day care.

Workload:

The average OPD attendance patients – visits per year are as follows:

  • New patients – 12000 patients per year.

RESIDENTS:

1) Dr.Bharat Soni
2) Dr.Nitin Gundre
3) Dr.Swarup Pal
4) Dr.Soumen Paul
5) Dr. Pranav Mali
6) Sayajirao Sargar
7) Dr.Supreet Marahe
8) Dr.Gauri Datar
9) Dr.V.Nagesh R
10) Nilesh Purkar
11) Dr.Nilesh Purkar
12) Dr.Shikha Gupta

Technical
  • Two Senior Technicians
  • Two Junior Technicians
  • Two Laboratory Assistants

 


Facilities, Equipments & Special services

  • OPD services
  • Indoor services
  • Bone marrow transplant (Autologous bone marrow transplant)
  • Bone marrow aspiration biopsies.
  • CBC, Coagulation profile and reporting
  • Comprehensive Hemophilia care centre.
  • Transfusion facility for Thalassemia patients.

Collaboration with IIH

ICMR has already recognized the 10 th floor hematology inpatient facilities of the Dr. J. C. Patel Hematology Department at the KEM Hospital as its clinical wing for the conduct of various research activities and drug trials. The following facilities are available to the Dr. J. C. Patel Department of Hematology from IIH [ICMR] for various collaborative projects

  1. Evaluation of routine hematology workup with automated particle counter for the study of various hematological disorders.
  2. Evaluation of Haemolytic Anemia, red cell enzyme studies and haemoglobinopathies including prenatal diagnosis.
  3. Evaluation of all bleeding and thrombophillic disorders including carrier detection and prenatal diagnosis.
  4. Evaluation of platelet function disorders, aggregometry and receptor studies.
  5. Evaluation of transfusion transmitted disorders, diagnosis of Hepatitis B, C and HIV 1+2 [Elisa & Western Blot]
  6. HLA tissue typing & cross-matching.
  7. Molecular biology techniques applied to different hematological disorders like PCR, Reverse Dot Blot Hybridization, etc.
  8. Haemopoietic stem cell isolation, invitro culture in semisolid and liquid media, long term one marrow culture.
  9. Hybridoma technology.
  10. Autoimmune disorder screening and detection of antiplatelet antibodies.
  11. Flow cytometry and surface marker studies for various hematological malignancies as well cell cycle studies of leukemic cells
  12. Red cell serology and grouping & crossmatching studies in the investigation of mismatched blood transfusion.
  13. Evaluation of Autoimmune Hemolytic anemia, screening and diagnosis.
  14. Intrauterine red cell transfusion in mothers with Rh sensitization.
  15. Study of chromosomal abnormalities in haemopoietic disorders.
  16. Evaluation of Iron overload with Serum Iron and ferritin studies.
  17. Evaluation of Megaloblastosis with Serum B12/Folate and DU suppression studies.

The IIH has a well equipped library with a good number of books, periodicals and Journals. It also has Medline on CD ROM as well as an Internet connection [TCP/IP account] for online search. It also subscribes to the Current Contents which are available on floppies for ready reference on the IIH computer network. It has an excellent audio visual conference hall facilities that are being used for interdepartmental teaching programmes.

For Students

The department offers the M.Ch Course of three years duration in Cardiovascular & Thoracic Surgery under the aegis of the Maharashtra University of Health Sciences Nashik. We have an intake of 4 students from this year. KEM Hospital is very often the first choice of PG students at the time of registration and this reflects the quantum and quality of training in the department. The residents go through a rigorous training programme aimed at attaining basic clinical and surgical skills. The residents rotate through other disciplines like Cardiology, Chest medicine, Vascular Interventional Radiology and Surgical Oncology at Tata Memorial Hospital. The department has an active teaching programme in the form of clinical presentations, journals club, diagnostic catheterization conferences and mortality meeting.The department also runs one year certificate course in the Extra Corporeal Perfusion Technology. The intake is of three students every year. The department also runs the lecture seriesand practical for BPMT course from MUHS. The department also given six months observation and training to the students recommended by the Bakkenn Institute.In addition, lectures are taken for Undergraduates, Physiotherapy and Occupational Therapy students, Nurses and others. The postgraduate students in Nursing from SNDT Women’s University spend a period of 3 months for practical training and research studies.

Ongoing projects

a) Safety and Efficacy of Intracoronary and Intramyocardial delivery of autologous bone marrow mononuclear cells in patients with triple vessel coronary artery disease and left ventricular dysfunction undergoing surgical revascularization.b) Randomized study to assess efficacy of three different ablative procedures to treat atrial fibrillation in patients with valvular heart disease.c) Research project submitted to DBT – Development of an experimental model employing vascular endothelial cells for its potential use in Tissue Engineered conduits.”

 

  • Recurrent multicentricsyndromicmyxoma. Under process for IHJ.
  • Giant mediastinal cyst with displaced mediastinum that turned out to be bronchogenic cyst. Under process IJCVTS.

Annual Report


Photo Gallery

Visit on 29 May 23 by Professor Joseph Muenzer, Pediatric Geneticist , University of North Carolina

Workshop on “Principles of Scientific Writing” 12, 13 October 2017, conducted for Pfizer Ltd

Mr Ashnik Chauhan at the DIA meeting in Chicago in June 2017

90 years of Seth GS Medical College and KEM Hospital, January 2016